|
Symbol Name ID |
Pparg
peroxisome proliferator activated receptor gamma MGI:97747 |
| Darker colors indicate more annotations |
| Human Phenotypes | Proteinuria |
Abnormality of the kidney |
Renal insufficiency |
Acute kidney injury |
Chronic kidney disease |
| Disease(s) Associated with PPARG | |||||
| pre-eclampsia |
| Mouse Phenotypes | increased mesangial cell number |
increased renal glomerulus apoptosis |
enlarged kidney |
increased kidney weight |
abnormal urine sodium level |
increased urine protein level |
albuminuria |
glomerulonephritis |
abnormal kidney morphology |
abnormal podocyte foot process morphology |
fused podocyte foot processes |
increased renal glomerulus basement membrane thickness |
abnormal renal glomerulus morphology |
expanded mesangial matrix |
renal glomerulus hypertrophy |
abnormal nephron morphology |
abnormal renal sodium ion transport |
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| Availability | Mouse Genotype | |||||||||||||||||
| Ppargtm1.1Gonz/Ppargtm1.1Gonz Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Ppargtm1.1Gonz/Ppargtm1.1Gonz Tg(Aqp2-cre)1Dek/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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